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Hailey L. Chapman

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Open access Sep 2026

Region-specific human cardiac extracellular vesicles differentially regulate mitochondrial function

Aim: The human heart contains two major mitochondrial subtypes, subsarcolemmal (SSL), fueling surface ion channels, and interfibrillar (IF), fueling interior contractile machinery. This study investigated whether the distinct extracellular vesicles (EVs) that we determined to be associated with these regions could infl...

Genevieve C. Sparagna, Christina M. Coughlan, Hailey L. Chapman et al. · 0 citations

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