Expression of cytochrome P450 (CYP96A146) from flixweed (Descurainia sophia) in Saccharomyces cerevisiae and metabolism of model substrates and herbicides
Findings suggest that the amino acid substitutions are likely responsible for the enhanced metabolic capability of CYP96A146-R, and may induce conformational changes of CYP96A146 enzyme, facilitating more frequent molecular collisions between CYP96A146 and the substrates or herbicides, thereby improving catalytic effic...