A Bioactive Constituent from Bazhen Decoction Alleviates Sepsis-Associated Liver Injury by Restoring SLC6A6-Mediated Taurine Transport to Reprogram Macrophage Immunometabolism.
ETHNOPHARMACOLOGICAL RELEVANCE Bazhen Decoction (BZD) is a classical formula first recorded in Ruizhu Tang Jing Yan Fang (14th century) and prescribed for centuries to replenish "Qi" and nourish "Blood". However, its bioactive constituents and immunometabolic mechanisms in sepsis-associated liver injury (SALI) remain u...