Author

Haiyi Chen

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Open access Aug 2026

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Findings uncover an OTUD7B‐STAT3 signaling axis that sustains microglial‐driven neuroinflammation and identify OTUD7B as a potential therapeutic target for mitigating neurodegenerative pathology in AD.

Lu-Yao Li, Hao Tang, Qin Yu et al. · Advancement of science · 0 citations

#computer vision Jan 2026

NavDB: A Comprehensive Database for Voltage-Gated Sodium Channels Modulators and Targets

NavDB is a specialized and open-access database focusing on VGSC modulators and targets that integrates 8023 curated data records covering 5168 compounds, including small molecules, toxins, drugs, and peptides, along with comprehensive annotations on biological activity, druggability, and structural feature.

Gaoang Wang, Jiahui Yu, Haiyi Chen et al. · Journal of Chemical Informat... · 0 citations