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Author

Halil Şenol

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Aug 2026

Rational design of thiazolidine-2,4-dione-integrated combretastatin A-4 analogues as potent and selective tubulin-targeting agents for triple-negative breast cancer.

The present study identifies compounds 2 and 3 as promising lead candidate that combines potent and selective antiproliferative activity, strong tubulin polymerization inhibition, and favorable binding characteristics compared with paclitaxel.

F. S. Tokalı, Şeyma Ateşoğlu, Pelin Tokalı et al. · 1 citation
Aug 2026

Synthesis, Computational Chemical Study, Molecular Docking, Dynamics Simulations, and Anti-Diabetic Potential of the Perfluorophenyl Acetamide Derivative

Results indicate this acetamide behaves as a competitive inverse agonist of 5-HT1B subtype receptor and the pharmacophore model of PFPA for interaction with 5-HT1BR was proposed.

Ulviyya Askerova, Gulnara Akverdieva, S. Demukhamedova et al. · 0 citations

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