The Utility of Cell-Free DNA (cfDNA) Fragmentomics as a Novel Biomarker for Early Cancer Detection: A Systematic Review of Analytical Validity and Clinical Potential
Background: Despite advancements in medicine, cancer still ranks among the top leading causes of death globally, especially in relation to the chances of survival, which are greatly influenced by early diagnostics. The existing approaches suffer from the necessity for invasive procedures, the resulting high cost associ...