Effect of Early Dexmedetomidine Addition on Prognosis in Mechanically Ventilated Patients Under Propofol Sedation: A Target Trial Emulation Study.
BACKGROUND Combination propofol-dexmedetomidine (DEX) therapy may affect patient prognosis. However, it remains unknown whether the effects of this combination depend on the timing of DEX initiation. OBJECTIVE This study aimed to investigate the association between early initiation of DEX and mortality in mechanicall...