Han-Chao Liu

Comparative single-cell transcriptomics highlights species-biased developmental trajectories and candidate regulatory modules in primate spermatogenesis.

Understanding primate testicular development is essential for elucidating the evolution of male fertility. Here, we integrated publicly available single-cell RNA sequencing datasets from 23 human and 4 macaque testes spanning infant to adult stages. Integrated analysis identified 22 conserved germ cell subtypes, includ...