Open access
Sep 2026
Activatable 19F NMR probes from drug scaffolds for assessing myeloperoxidase-associated inflammation
Myeloperoxidase (MPO)-derived hypochlorous acid (HClO) is a key oxidant in inflammatory diseases such as sepsis and neuroinflammation. Selective detection of MPO-derived HClO in complex biological matrices remains challenging. 19F NMR spectroscopy offers zero-background, environment-sensitive chemical shifts and easy q...
Xiang-Jie Luo, Xin-Ran Ji, Zhuo-Ying Chen et al.
· Chemical Science · 0 citations