Han-Hong Fang

The aging secretome as a candidate driver of bone remodeling imbalance: myokines, adipokines, and senescence-associated secretory factors

The aging secretome should be viewed as an organizing framework whose individual pathways and relative contributions require further validation in human bone, and provides a common context for comparing pathway-specific interventions, such as activin type II receptor blockade and sclerostin inhibition, with broader app...