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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Han Liu

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Jul 2026

Active Pocket Remodeling Coupled with Substrate Tunnel Engineering of ω-Transaminase CC1012 for Efficient Synthesis of (S)-1-Boc-3-aminopiperidine.

Transaminases provide an effective approach for the asymmetric synthesis of chiral amines. However, native ω-transaminases often suffer from low catalytic efficiency and poor substrate concentration tolerance, limiting industrial applicability. Targeting the synthesis of (S)-1-Boc-3-aminopiperidine, this study engineer...

Meng Xu, Han Liu, Guangyu Lin et al. · 0 citations

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