Author

Han-Mei Li

2 papers indexed here

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Open access Oct 2026

Ultrasound-Triggered HSC Membrane-Cloaked Nanotherapeutics Attenuate Liver Fibrosis via Simultaneous Modulation of Mitophagic Flux and the TGF-β/Smad3 Cascade.

This study presents an ultrasound-triggered therapeutic platform based on melatonin-loaded and perfluoropentane-encapsulated mesoporous silica nanoparticles, which are further cloaked with activated hepatic stellate cell membranes (HM-Mel@PFP-MSNs), designed for the precision treatment of liver fibrosis. This innovativ...

Han-Mei Li, Li-Tao Ye, Yi-Han Leng et al. · ACS Biomaterials Science & E... · 0 citations

Open access Sep 2026

Reprogramming M2 macrophages via TLR7/8 agonist-loaded hollow MnO2 nanovehicles to suppress the progression of liver cancer

As a prevalent malignancy, liver cancer ranks as the third most common cause of cancer mortality globally. Within the tumor microenvironment, tumor-associated macrophages (TAMs) exhibit contrasting functional phenotypes: the anti-tumor M1 type and the pro-tumor M2 type. Reprogramming TAMs from the M2 to the M1 phenotyp...

Pei-Pei He, Zheng-Ju Hou, Han-Mei Li et al. · PLoS ONE · 0 citations