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Han-Qing Yao

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Open access Sep 2026

Knockdown of SENP7 attenuates cognitive impairment in offspring mice induced by maternal sevoflurane anesthesia partially through cGAS/STING/IRF3-mediated pyroptosis

Exposure to sevoflurane (SEV) during pregnancy is associated with long-term cognitive impairment in offspring; however, the precise mechanisms remain unclear. This study aimed to investigate the role of Sentrin/SUMO-specific peptidase 7 (SENP7) and its downstream pathways in SEV-induced neurotoxicity. Preg...

Jin-Teng Du, Xue Ma, Ke-Qin Hua et al. · 0 citations

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