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Author

Han Wang

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Open access Jul 2026

Resveratrol-activated PI3K/AKT/mTOR signaling pathway attenuates ferroptosis by promoting NRF2/GPX4 metabolic pathway to mitigate IFN-gamma-mediated aplastic anemia

RSV is a potential therapeutic drug for ferroptosis-related AA treatment by targeting the PI3K/AKT/mTOR signaling pathway, which enhances NRF2-mediated GPX4 transcription, thereby ameliorating AA symptoms in vitro and in vivo.

Erhao Zhang, Jia-Nan Cui, Xinran Zhu et al. · 0 citations

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