Open access
Sep 2026
HDX-MS-Guided computational modeling for rapid and accurate antibody-antigen interface mapping
A hydrogen-deuterium exchange mass spectrometry (HDX-MS)-guided structural modeling workflow for efficient and accurate epitope and paratope mapping across three prospective case studies in therapeutic protein discovery and engineering is presented.
William P. McMahon, Han-Zhi Zhang, Xiu-Ling Li et al.
· mAbs · 0 citations