Author

Hang-ping Yao

3 papers indexed here

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Review Open access Oct 2026

Targeting receptor tyrosine kinases: from molecular mechanisms to clinical therapeutics

Receptor tyrosine kinases (RTKs), constituting a major family of cell-surface transmembrane receptors, are essential for intracellular tyrosine phosphorylation and signal transduction. RTK signaling is crucial for cellular fate regulation and tissue homeostasis, and its disruption is linked to numerous diseases. Herein...

Kai Wu, Jia Ji, Ting Sun et al. · Signal Transduction and Targ... · 0 citations

Open access Oct 2026

Propionate promotes CD8+ T-cell infiltration and enhances immunotherapy efficacy in colorectal cancer

Abstract Background Short-chain fatty acids (SCFAs) produced by the gut microbiota are increasingly recognized as regulators of host immunity, yet the role of individual SCFAs in shaping the tumor immune microenvironment in colorectal cancer (CRC) remains poorly defined. This study aims to investigate the role of propi...

Jing-Ying Pan, Le Tong, R. Fei et al. · Journal for ImmunoTherapy of... · 0 citations

Open access Aug 2026

A bispecific antibody targeting conserved hemagglutinin epitopes confers broad protection against H7 avian influenza and accelerates viral clearance via localized respiratory delivery

ABSTRACT The continuous antigenic drift of zoonotic H7 avian influenza viruses remains a significant global public health threat. While monoclonal antibodies (mAbs) targeting the hemagglutinin (HA) head offer potent neutralization, their efficacy is often undermined by rapid viral escape. In this study, we systematical...

Han Wu, Fan Yang, Ping Wang et al. · Emerging Microbes and Infect... · 0 citations