A closed-loop paradigm for precision oncology: Integrating dynamic monitoring, organoid models, and explainable AI.
BACKGROUND Precision oncology faces three systemic bottlenecks: static molecular snapshots fail to capture tumor dynamics, patient‑derived organoids lack physiological reconstruction of the tumor microenvironment (TME), and artificial intelligence (AI) remains a "black box" in clinical decision‑making. This review aims...
Ya-Nan Liu, Ya-Ping Wang, Xiao-Xia Huang et al.
· Pharmacological Research · 0 citations