Apical extracellular matrices (aECMs) act as barriers against pathogens and shape tissue organization throughout animals. In nematodes, the cuticle is the aECM performing this function, representing a defining feature of this largest animal phylum. Morphological and molecular evidence supports that worm cuticles extend...
Lin-Xuan Li, Kai-Yu Qiu, Hanh Witte et al.· Journal of Biological Chemis...· 0 citations
To maximize their reproductive success, nematodes not only must arrest their development in response to adverse growth conditions but also must quickly recover if conditions improve. However, the molecular signals that coordinate these transitions remain poorly understood. Here, we show that a hybrid polyketide synthas...
Kevin Mai, Chi-Su Yoon, Dilip V. Prajapati et al.· Nature Communications· 0 citations
The evolution of brains is subject to investigation in many different animal groups, each offering unique advantages to advance our understanding of the cellular, molecular and regulatory substrates of evolutionary change. Here, we use two nematode species, C. elegans and P. pacificus, separated by more than 200 millio...
Yasmin H. Ramadan, Curtis M. Loer, Hyunsoo Yim et al.· bioRxiv· 0 citations
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