Hani Moslem Ahmed

FOXM1 as a candidate dosage rheostat and state selector in breast cancer: linking multilevel regulation to adaptive plasticity and therapy resistance

FOXM1, a forkhead-box transcription factor, is consistently overexpressed in breast cancer, particularly in the basal-like and triple-negative subtypes, in which high expression predicts poor survival. We propose, as a falsifiable hypothesis rather than an established mechanism, that FOXM1 may function as a dosage-inte...