Hannah B. McDowell

Endometriosis-derived iPSCs reveal conserved stromal maturation and endocrine responsiveness

Endometriosis is a chronic, hormone-dependent disease characterized by altered endometrial stromal function, but mechanistic and translational studies have been hindered by the lack of tractable human models. Here, we establish an induced pluripotent stem cell (iPSC)–based platform derived from patients with endometrio...