Hannah Haneke

Host TLR4 activation by tenascin-C is associated with MMP14-dependent glioma invasion

Glioblastoma is the most aggressive primary brain tumor in adults and is characterized by diffuse invasion and profound remodeling of the tumor microenvironment. Tumor-associated microglia and macrophages represent the largest non-malignant population in glioblastoma and promote invasive growth through context-dependen...