Hans K. Carlson

Genome-wide fitness profiling reveals flagellar rotation as an energetic liability during anaerobic maintenance in Pseudomonas aeruginosa

The results show that in a low-powered maintenance state, limiting energy-dissipating processes, such as proton-motive force loss through flagellar rotation, supports cell survival, and suggest that growth-arrested cells live at a bioenergetic knife’s edge, where an energy-dissipating process can tip the balance betwee...