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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Hanzheng Wang

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Open access Aug 2026

PRDM5 regulates ASK1 transcription to affect macrophage inflammation, lipid accumulation and apoptosis progression.

PRDM5 serves as a common susceptibility gene for ASCVD and facilitates macrophage pathogenic phenotypes via the ASK1/JNK/NF-κB cascade, with significantly upregulated expression in monocytes and plaque tissues from patients.

Meng Sun, Han Sun, Hanzheng Wang et al. · 0 citations

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