Author

Hao Chen

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Open access Aug 2026

ZCCHC4 promotes replication-dependent histone mRNA translation through interaction with the eIF3 complex

This study establishes a previously unrecognized role for ZCCHC4 in histone synthesis, at least in part through its interaction with eIF3, thereby sustaining histone supply during S phase in tumor cells and point to a potential role for ZCCHC4 in tumorigenesis.

Ruiqi Wang, Xiaoyan Shi, Yang-Yi Zhang et al. · Cell Death Discovery · 0 citations