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Open access Sep 2026

Gut microbial H2S promotes metabolic dysfunction in mice via hepatic PPARα suppression.

This study investigates the role of gut microbiota-derived hydrogen sulfide (H2S) in obesity and glucose metabolism disorders. By integrating human gut metagenomic data, intervention experiments in mouse models, and in vitro cellular assays, we identified a signature of microbial sulfur metabolism in human cohorts and...

Shi-Bo Lei, Xuan Qiu, Zhen Wang et al. · 1 citation

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