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Open access Oct 2026

HMGA2 Stabilizes hnRNPK to Drive YAP-Dependent Liver Metastasis in Pancreatic Cancer

The findings establish the HMGA2/hnRNPK-YAP axis as a critical regulator of LM and propose targeting this pathway as a promising therapeutic strategy for metastatic PC.

Yu Xie, He-Xing Hang, Hao-Bai Liu et al. · 0 citations
Open access Aug 2026

Exploration of the mechanism of gut microbiota-mediated immune modulation in the pathogenesis of pancreatic cancer

A genetically predicted causal pathway linking immune cell phenotypes to pancreatic cancer via specific gut microbiota via specific gut microbiota is supported, underscore the mediating role of certain microbial taxa and offer novel insights for future strategies involving immune modulation or microbiota-based interven...

Meng-Yun Cai, Hao Cheng, Yaying Jia et al. · 0 citations
Aug 2026

High-Dimensional SERS Mapping of Single Circulating Tumor Cells Deciphers the Phenotypic Landscape and Stratifies Metastatic Risk in Pancreatic Cancer.

Applying PRISM to CTCs from pancreatic cancer patients, a novel data analysis framework is introduced, including a 'Metastasis Potential Score' (MPS), to translate high-dimensional spectral data into a clinically relevant metric for risk stratification.

Yanrong Wen, Mengxiang Liu, Chun-Hui Liu et al. · 0 citations

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