Hao-Dong Wang

Targeting DPP9 attenuates podocyte injury by regulating NRF2 antioxidant signaling

Introduction Podocyte injury is a critical event in the progression of chronic kidney disease (CKD), with oxidative stress as a central pathogenic mechanism. Despite the efficacy of finerenone in mitigating CKD progression, its precise cytoprotective mechanisms within podocytes remain incompletely defined. This study a...