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Author

Haohao Gao

2 papers indexed here

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Review Open access Aug 2026

The Heart–Kidney Axis in Heart Failure and Chronic Kidney Disease: Mechanisms, Mediators, and Therapeutic Implications

The heart–kidney axis has emerged as a central framework for understanding the bidirectional interactions that drive cardiorenal syndrome and broader cardiovascular–kidney–metabolic (CKM) disease. However, existing interpretations have often emphasized hemodynamic and neurohormonal mechanisms without fully integrating...

Ao-Di Fan, Xin-Wei Chen, Ke Yang et al. · 0 citations
Review Open access Aug 2026

TREM2 signaling in cardiovascular disease: macrophage heterogeneity, timing, and therapeutic opportunity.

This review systematically delineates the spatiotemporal dynamics and functional duality of TREM2+ macrophages across major cardiovascular conditions, and further evaluates the current evidence and limitations of soluble TREM2 (sTREM2) as a candidate biomarker and critically appraises translational strategies targeting...

Ke Yang, Xue-Fang Ma, Bin-Yan Wang et al. · 1 citation

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