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Review Open access Aug 2026

Advances in understanding the tumor microenvironment of neuroendocrine prostate cancer

Neuroendocrine prostate cancer (NEPC) is an aggressive, treatment-refractory phenotype of advanced prostate cancer. This narrative review was informed by targeted searches of PubMed, Web of Science through May 2026. We classify evidence as Level A (human NEPC samples or clinical cohorts), Level B (NEPC-specific models)...

Nan Yao, Qi-Xing Yang, Peng-Kang Chang et al. · 0 citations
Open access Jul 2026

FOXA2 suppresses ESCC proliferation and metastasis by inhibiting PSMB9 expression, thereby attenuating proteasome activity.

BACKGROUND Esophageal squamous cell carcinoma (ESCC) represents a highly lethal malignancy. The FOXA2 was involved in cellular proliferation, differentiation, tumorigenesis, and metastasis. The precise regulatory mechanisms of FOXA2 in ESCC progression remain unclear. MATERIALS AND METHODS Western blotting, reverse t...

Wenqiang Xia, Ning Li, Chunxia Gong et al. · 0 citations

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