Aug 2026
HighMorph: De Novo Cyclic Peptide Sequence Design via Protein-Protein Interaction Recapitulation.
HighMorph is presented, an interaction-guided framework that combines protein–protein interaction information with artificial intelligence for rational cyclic peptide design and provides insights for developing therapeutics targeting challenging protein interfaces.
M. Lan, Cheng-Yun Zhang, Wentong Wang et al.
· Journal of Medicinal Chemist... · 0 citations