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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Hao-Nan Fang

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Review Open access Oct 2026

Steroid 5α-reductase type 1 as a neurodevelopmental toxicological target: Hydrophobicity governs environmental inhibition within, but not across, chemical classes.

Steroid 5α-reductase type 1 (SRD5A1) catalyzes the rate-limiting reduction of progesterone to 5α-dihydroprogesterone, the committed step toward allopregnanolone, a positive allosteric modulator of γ-aminobutyric acid type A (GABAA) receptors. Its clinical relevance is shown by allopregnanolone therapeutics for postpart...

Xin-Miao Lu, Jia-Qi Chen, Hao-Nan Fang et al. · 0 citations
Open access Sep 2026

Tetrachlorobisphenol A inhibits steroidogenesis in pubertal rat Leydig cells through disruption of copper homeostasis.

Tetrachlorobisphenol A (TCBPA) is a widely used flame retardant with potential endocrine-disrupting properties. This study investigated the effects of TCBPA on steroidogenesis in pubertal rat Leydig cells, focusing on copper homeostasis and on whether the cuproptosis pathway is engaged. Male Sprague-Dawley rats (35 day...

Pu-Tian Zhang, Hao-Nan Fang, Zi-Jian Lin et al. · 0 citations

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