Open access
Aug 2026
PDLIM2 Promotes Osteogenesis of Adipose-Derived Stem Cells by Modulating β-Actin-Dependent Wnt/β-Catenin Signaling.
BACKGROUND Bone tissue possesses strong regenerative potential, but large segmental bone defects often exceed its intrinsic capacity for self-healing. Human adipose-derived stem cells (hASCs) offer a promising cellular basis for bone regeneration owing to their robust osteogenic differentiation potential. However, the...
Yu-Lian Shi, Ting-Yu Fan, Rong-Mei Qu et al.
· Frontiers in Bioscience · 0 citations