Author

Hao-Ran Huang

2 papers indexed here

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Open access Aug 2026

ChemIntelligence Enables Antibody-Free, Ultra-Low-Input Profiling of Lysine Lactylation and Diverse Acyl-Proteomes

Lysine acylations, including lactylation (Klac), are pivotal regulators of cellular physiology. However, their analysis is currently bottlenecked by antibody enrichment strategies that suffer from sequence bias and require milligram-scale protein inputs, severely precluding the profiling of scarce clinical biopsies and...

Chang Shao, Zimeng He, Qi Yuan et al. · bioRxiv · 0 citations

Review Open access Oct 2026

Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies

ABSTRACT Cancer metastasis is a spatiotemporal dynamic process jointly driven by the intrinsic evolution of cancer cells and continuous microenvironmental selection, rather than a simple linear accumulation of genetic alterations. The metastatic diversity of cancers is driven by heterogeneity in physicochemical propert...

Yu-Peng Zhao, Wen-Chao Xu, Yi-Bo Wang et al. · MedComm · 0 citations