Open access
Oct 2026
TNFAIP3 suppresses lactylation-associated DNA damage repair and enhances chemosensitivity in ovarian cancer
Ovarian cancer (OC) remains one of the most lethal gynecologic malignancies due to extensive metabolic plasticity and rapid development of platinum resistance. Lactylation, a lactate-derived post-translational modification, has emerged as a critical regulator linking tumor metabolism to cellular signaling. Howeve...
Hui-Xia Huang, Lei-Mei Xu, Xi Cheng et al.
· Cellular Oncology · 0 citations