Depression and Longitudinal Frailty Trajectories in Middle-Aged and Older Adults with Chronic Pain: A 8-Year National Cohort Study in China
Background Global population aging is accelerating, and pain and depression frequently co-occur in middle-aged and older adults. Frailty, an age-related clinical syndrome, markedly elevates the risks of falls, disability, hospitalization, and mortality. This study investigated whether comorbid depression affects long-t...