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Hao Yao

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Review Open access Aug 2026

Advances, challenges, and innovative strategies of CAR-T cell therapy in pancreatic cancer

Overall, CAR-T therapy for pancreatic cancer is progressing from preclinical exploration toward clinical translation, with a focus on representative tumor-associated targets, particularly MSLN and CLDN18.2, which show promising antitumor activity; however, durable clinical responses remain difficult to achieve.

Ru-Yan Xiao, Ye-Fan Jiang, Wei Zhao et al. · 0 citations

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