Open access
Jul 2026
Single-cell expression quantitative trait locus Mendelian randomization reveals immune cell-specific causal regulatory networks and actionable targets in polycystic ovary syndrome
This sc-eQTL MR study reveals immune cell-specific causal regulatory networks in PCOS, where GLIPR1 in non-classical monocytes represents a high-confidence protective target, while XBP1 provides suggestive evidence for immune-mediated pathogenesis.
Jia-Huan Zhang, Yi-Kai Liu, Dan-Hong Lin et al.
· Science in progress · 0 citations