Author

Hao-Yi Yang

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Open access Aug 2026

TRIM41 stabilizes RBPJ through K63 linked ubiquitination and promotes stemness of hepatocellular carcinoma cells.

Persistent activation of the Notch signaling pathway is closely associated with the maintenance of cancer stem cells (CSCs) and the progression of hepatocellular carcinoma (HCC). Recombination signal binding protein for immunoglobulin kappa J region (RBPJ), a key transcription factor that mediates downstream target gen...

Hao Wu, Jin-Qiao Wu, Xin-Yu Zhang et al. · Cellular Signalling · 0 citations

Aug 2026

Disruption of RBPJ in liver cancer-infiltrating T cells enhances antitumor immunity through remodeling epigenetic landscape.

B. Pan, Jin-Qiao Wu, Shuyan Zhou et al. · Cell Death and Differentiati... · 0 citations

Open access Jul 2026

NRGN inhibits CD8⁺ T cell effector function by downregulating MHC-I expression through the FMR1-IRF8 axis in hepatocellular carcinoma.

Modulation of the NRGN-IRF8-MHC-I axis could represent a potential strategy for improving immunotherapeutic responses and sustain suppression of antigen presentation in HCC.

Dong-Jie Ye, Jiacheng Qiu, Hao-Yi Yang et al. · Journal of experimental & cl... · 0 citations