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Author

Hao-Yu Wu

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Open access Oct 2026

IL‑18 improves the expansion and functional fitness of human Vδ1 T cells for superior solid tumor immunotherapy

Human Vδ1 T cells represent promising candidates for allogeneic adoptive immunotherapy due to their MHC-independent tumor recognition and inherent tissue tropism. However, their clinical translation is hampered by their low frequency in peripheral blood and the challenge of generating sufficient functional cells...

Shun-Tian Chen, Lu-Jie Zhao, Xin-Rui Xie et al. · 0 citations
Jul 2026

A fast 2C-induction method reveals a barrier role of SP2 for totipotency

This study has established a highly efficient in vitro model for totipotency induction and highlighted molecular barriers shaping cell fate decisions, providing a platform to dissect the mechanisms governing the pluripotency-to-totipotency transition.

Siling Hu, Ping-Hui Zhu, He Liu et al. · 0 citations

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