Author

Hao-Ze Zhang

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Review Open access Sep 2026

The potential role and research progress of the gut microbiota–NGF axis in postmenopausal bone homeostasis imbalance

Postmenopausal osteoporosis(PMOP)is a common metabolic bone disease characterized by an imbalance in bone remodeling due to estrogen deficiency. Increasing evidence suggests that alterations in gut microbiota, intestinal barrier, immune response, microbial metabolites, and autonomic nervous activity are involved in pos...

Yang-Yang Chen, Ding-Peng Li, Zhong Wang et al. · Frontiers in Immunology · 0 citations

Review Open access Sep 2026

Intestinal–Bone Axis Mediated by Bifidobacterium: Mechanistic Analysis and Therapeutic Potential in Osteoporosis

Osteoporosis is one of the most prevalent metabolic bone diseases worldwide, and current pharmacological options are limited by adverse effects and are poorly suited to long-term use, underscoring the need for novel therapeutic targets. Bifidobacterium, one of the most representative beneficial bacterial genera in the...

Fa-Dong Li, Hao-Ze Zhang, Bo-Ran Zhang et al. · Microorganisms · 0 citations