A biocompatible and colon-targeted oral delivery platform based on maize starch and alginate for enhancing probiotic efficacy in ulcerative colitis management.
Probiotics help treat ulcerative colitis (UC) by stabilizing gut microbiota, strengthening the mucosal barrier, and modulating immune responses, yet their viability plummets in the harshly acidic stomach. To overcome this limitation, we engineered a colon-targeted, double-layer oral delivery system in which Lactobacill...