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Haojun Chen

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#diffusion models Open access Aug 2026

Eco-Evolutionary Dynamics of Proliferation Heterogeneity: A Phenotype-Structured Model for Tumor Growth and Treatment Response

Abstract Intra-tumor heterogeneity in proliferation rates fundamentally influences cancer progression and treatment resistance. To investigate how continuous phenotypic variation shapes eco-evolutionary dynamics, we develop a phenotype-structured partial differential equation framework that explicitly models proliferat...

Lara Schmalenstroer, Haojun Chen, Russell C. Rockne et al. · 0 citations

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