Haomiao Su

MIAO-ORF: Mixture-aware Inference of Alternative-frame ORFs

MIAO (Mixture-aware Inference of Alternative-frame ORFs) detects translated alternative-frame internal open reading frames (intORFs) from ribosome-profiling data. Its codon-level Dirichlet–multinomial model tests whether phase counts are better explained by host-CDS translation alone or by a mixture of host and alterna...