Chronic kidney disease (CKD) is a frequent and lethal comorbidity in patients with acute myocardial infarction (AMI). This study aimed to quantify the clinical impact of CKD on post-MI outcomes and investigate the molecular mechanisms of cardiorenal crosstalk involving FKBP5.
We analyzed MI populations fro...
W. Zhang, X. Gao, J.-M. Chen et al.· European Heart Journal· 0 citations
Optimal Life’s Essential 8 cardiovascular health is associated with lower risk of MACEs and CKD progression in ASCVD patients, with smoking and glucose as primary modifiable drivers of residual risk for MACEs, and glucose, BMI and smoking for CKD.
Z. Yuan, X. Lu, G. Yuan et al.· European Heart Journal· 0 citations
Higher LE8 scores were associated with lower risks of MACE and CKD in ASCVD patients, and high LE8 achievement may attenuate risks toward non-ASCVD levels.
This study reveals that SRA1 is a novel therapeutic target for PPD, which enhances the understanding of its molecular aetiology and the development of therapeutic strategies.
Ming Chen, Qinlin Wei, Hao-Wen Li et al.· npj Mental Health Research· 0 citations
Findings highlight significant sex differences in the effect of depression on CHD risk, which could inform sex-specific preventive strategies for reducing the cardiovascular burden in individuals with depression.
Haozhang Huang, Ming Chen, Xiao-Zhao Lu et al.· European Journal of Preventi...· 0 citations
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