Author

Harendra Kumar

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Review Open access Aug 2026

Risk-adapted first-line therapy selection in advanced EGFR-mutant NSCLC: a practical clinical algorithm integrating tumor biology and patient factors

Advanced EGFR-mutant non-small cell lung cancer (NSCLC), specifically tumors harboring classical activating mutations (exon 19 deletions and L858R substitutions, which are the exclusive focus of this review), is no longer a single-treatment landscape. The MARIPOSA and FLAURA2 phase 3 trials have established that combin...

Ashish Sharma, J. Tan, Harendra Kumar et al. · Medical Oncology · 0 citations

Review Open access Aug 2026

Tissue and blood-based predictive biomarkers in hepatocellular carcinoma immunotherapy: synthesis of 2023–2026 evidence and a proposed clinical integration framework

A narrative review synthesizes evidence published between 2020 and 2026 within a unified clinical framework not provided by prior reviews, and proposes an original biomarker-guided clinical algorithm, a comparative clinical readiness table, and a disease-continuum biomarker timeline as practical tools for clinicians an...

Ashish Sharma, J. Tan, Rajvardhan Sisodia et al. · Frontiers in Oncology · 0 citations