Formulation And Evaluation Of Mucoadhesive Microspheres Of Tramadol For Nasal Delivery
The objective of the present study was to develop and evaluate mucoadhesive microspheres of Tramadol hydrochloride for nasal delivery to enhance its bioavailability and provide rapid onset of action for pain management. Tramadol, a centrally acting analgesic, undergoes extensive first-pass metabolism when administered...