2026
Synergetic inhibition of deubiquitinases and acetyltransferases to regulate tau acetylation and aggregation in SH-SY5Y cell line model of Alzheimer's disease.
The development of standardized cell culture models in the SH-SY5Y neuronal system will be crucial to evaluating the therapeutic potential of this synergetic inhibition strategy, thereby restoring ubiquitination and promoting tau degradation.
Basavaraju K. C., Harshitha D. K., Poornima Priyadarshini
· Methods in Enzymology · 0 citations