Hassan Abdul Aziz Dhedhi

Efficacy and safety of zilebesiran in adults with hypertension: a systematic review and meta-analysis of randomized controlled trials

Hypertension is a major modifiable risk factor for cardiovascular disease, yet global control rates remain low. Zilebesiran, an investigational RNA interference therapy, targets angiotensinogen to modulate the renin–angiotensin–aldosterone system. While previous reviews exist, updated evidence is needed to better chara...