Experimental and theoretical approaches on structural, electronic, thermal and conductivity properties of ethynylated versus alkoxylated chalcones and elucidation of their cytotoxicity mechanisms in Acanthamoeba cells.
The new members of ethynylated and alkoxy chalcone derivatives (4TDEP and 4HPEP) featuring donor-π-Acceptor (D-π-A) and donor-π-Donor (D-π-D) systems were successfully designed and synthesized via Claisen-Schmidt condensation reaction. The physico-chemical properties of these molecules were determined via FTIR, 1H and...