Open access
Aug 2026
Synthetic Heparan Sulfate-like Oligosaccharides as Tools to Decipher Growth Factor Recognition
In NIH3T3 fibroblasts, compound 8 selectively reduced FGF2-induced proliferation in a dose-dependent manner without measurable cytotoxicity, highlighting aminoglycoside-derived HS mimetics as synthetically accessible platforms for modulating growth factor signaling.
Joseph Wakpal, Kartikey Singh, M. Hotor et al.
· Journal of Medicinal Chemist... · 0 citations